Cleveland Fed President Loretta Mester said she doesn't see evidence that inflation has peaked and is on board with supporting multiple rate increases.
The openings total declined by 455,000 from the upwardly revised March number to 11.4 million in April, according to the Job Openings and Labor Turnover Survey.
Treasury Secretary Janet Yellen emphasized that the White House has several strategies that will reduce inflation she conceded is too high for Americans.
The Fed's preferred inflation gauge rose 4.9% in April from a year ago, a still-elevated level that nonetheless indicated that price pressures could be easing.
The U.S. economic contraction to start the year was worse than expected as weak business and private investment failed to offset strong consumer spending.