"At some point, we are likely to see community spread in the U.S. or in other countries," said Dr. Nancy Messonnier, director of the CDC's National Center for Immunization and Respiratory Diseases.
Earlier, Hubei province said it is starting to include "clinically diagnosed" cases in its figures and that 13,332 of the new cases fall under that classification.
On Tuesday, CDC officials said an evacuee from Wuhan was re-committed to UC San Diego Health for further medical care and isolation after being accidentally released due to a mishandling of test results.
The CDC said Thursday the first 195 American evacuees from Wuhan were released on Tuesday from March Air Reserve Base in Riverside, California, and that more than 600 people remain in quarantine.
World health officials are scrambling to determine just how widespread the new coronavirus is as Chinese authorities reported a surge in new cases overnight.
China's Hubei province on Thursday reported a spike in the number of new coronavirus cases. The province said it started to include "clinically diagnosed" cases in its tally.
New coronavirus cases in China appear to have stabilized in recent days, but world health officials cautioned the public against reading too much into those numbers.
Read the latest stock market news and analysis on Asia Pacific in regions from Japan, China, Singapore, Australia, to New Zealand. Find business; finance; economy, stocks, and global economy news on CNBC's Asia Pacific page.