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Lin-Manuel Miranda, creator of the hit musical "Hamilton," premiered a public service announcement Tuesday night to encourage people to get out and vote.

Here's what you need to know about the markets before you start your business day.

In Tokyo autumn leaves pop in mid- to late-November. Here are the best places to see them.

Sophia Neophitou, editor-in-chief of 10 Magazine, shares her best moments from Paris Fashion Week Spring-Summer 2017.

Contemporary surrealists manipulate everyday objects and motifs to create a playful, warped spin on reality.

Diane James, who replaced Nigel Farage as the leader of the UK Independence Party, has stepped down after just 18 days on the job.

Conservationists fear for the survival of the rare pangolin which is thought to be the most trafficked animal in the world. CNN investigates what is being done to save it.

Virginia Sen. Tim Kaine attacked both Donald Trump and Mike Pence for their praise of Vladimir Putin during Tuesday's vice presidential debate.

Photographer Peter Lindbergh shot some of the most recognizable photos of '90s supermodels, including Kate Moss, Naomi Campbell and Cindy Crawford.

Peniel Joseph says the struggle for black dignity in the nation's criminal justice system took center stage during the vice presidential debate.

Republican vice presidential nominee Mike Pence called Tuesday night for the US to be willing to use the military to hit the Syrian regime and to establish safe zones to protect civilians.

Mike Pence demonstrated the benefit of preparing for a debate -- the question is whether Donald Trump will heed the lesson.

Mike Pence drew the ire of Latino groups Tuesday night, when he accused rival Tim Kaine of relying on the same attacks that have been used against Republican nominee Donald Trump.

A new study projects that $3 billion worth of the most common cancer medicines will go to waste this year in the United States.

Should men be routinely screened for prostate cancer? This question has been asked ever since the prostate specific antigen test, or PSA, became widely available more than two decades ago.

In the first and only vice presidential debate of 2016, the second fiddles took center stage. Their conversation at times, however, might be described as just a little out of tune.

Donald Trump's son, Eric, said Tuesday night that the Republican presidential nominee pays a "tremendous amount of tax" after being asked to put to rest questions about whether his father has paid federal income taxes in recent years.

Indiana Gov. Mike Pence and Virginia Sen. Tim Kaine took the biggest stage of their careers Tuesday night, but their well-established records were a clear a back seat to those of their running mates: Donald Trump and Hillary Clinton.

Florida Gov. Rick Scott and North Carolina Gov. Pat McCrory declared states of emergency as Hurricane Matthew churned north.

Hurricane Matthew brought powerful winds and heavy rains to Haiti Tuesday morning. The dangerous Category 4 hurricane is packing winds of 145 mph as it heads toward Cuba.