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Real-time nanoscale imaging reveals differences in antibody access to cancer-linked proteins on tiny vesicles

2 days 7 hours ago
Researchers at the Nano Life Science Institute (WPI-NanoLSI) at Kanazawa University have developed a way to observe how antibodies interact with a cancer-related protein carried on tiny membrane-bound vesicles released by cells. Using high-speed atomic force microscopy, they found that measuring how much of the protein is present does not necessarily show how accessible it is to antibodies. The findings reported in the journal Small Methods provide a new way to investigate differences between individual cancer-derived vesicles although further research is needed before the approach can be used clinically.

Owners who spend more time close to their cats tend to have more positive moods

2 days 7 hours ago
Many owners will enthusiastically attest that their cat has improved their quality of life. Some studies support this common claim that caring for a feline friend has positive effects on human health and well-being. However, the evidence is inconsistent, and other studies have even reported possible negative effects of cat ownership.

Exchange rates react immediately to the threat of tariffs

2 days 8 hours ago
Exchange rates are more than just abstract numbers. They determine the value of a Mexican peso, the cost of a German car in the U.S. and whether an Argentine farmer can repay his debts. Jantke de Boer, junior professor of international monetary macroeconomics at Ruhr University Bochum, has examined how expectations of future protectionist measures influence exchange rates.

Tiny molecular changes, big microparticle deformation

2 days 8 hours ago
Materials that change their shape upon exposure to light are attracting growing interest in applications such as soft robotics, microscale actuators and smart materials. However, the connection between molecular-level structural changes and larger-scale deformation remains incompletely understood.

Resistance to change has 12 different drivers, new measurement tool reveals

2 days 10 hours ago
Almost all change is difficult: adapting your lifestyle, a reorganization at work, or starting to use gender-neutral language. When behavioral change is required, resistance is therefore often encountered. As a result, it can sometimes take a long time for a change to be accepted—and sometimes it doesn't happen at all. It is therefore important to understand where that resistance comes from, according to Radboud University communication scientist Marieke Fransen. Fransen and her colleagues investigated this and identified 12 reasons.

Performance under pressure: A new perspective on why we fail—or rise to the occasion

2 days 14 hours ago
The decisive penalty kick in a final, match point in tennis or the last attempt in a competition: When a lot is at stake, even a well-practiced performance can suddenly break down. Yet pressure does not necessarily impair performance. Some people perform at their best precisely in the moments that matter most. Existing accounts can only partly explain why.

First in-depth map of 'forever chemicals' in the Finger Lakes created

2 days 16 hours ago
In 2023, professor Damian Helbling was getting a lot of calls and emails from local residents. The Environmental Protection Agency (EPA) had just announced regulations to limit per- and polyfluoroalkyl substances (PFAS)—some of which have been linked to cancers and other negative health effects—in drinking water. Ithacans and others in the region wanted to know about levels in the ponds, lakes, streams and creeks in their proverbial backyards.

Endangered species in Canada face extensive delays receiving protection

2 days 17 hours ago
For more than 20 years, Canada's Species at Risk Act (SARA) has protected wildlife that are at risk of being lost from Canadian lands and waters. Once a species is listed as extirpated, endangered or threatened under the act, it becomes illegal to kill, harm or capture it or damage its residences. Its critical habitat must also be protected, at least on federal land.

Can extra weight weigh on your dog's brain?

2 days 19 hours ago
Scientists have learned a lot about what happens to the human body as we age. But there's still much to learn about how other species age, including dogs. Even carrying extra weight could affect a dog's cognitive health. Alexandra Genualdi, a student at Oklahoma State University who presented her research in September at the American Physiological Society's 2026 Comparative Physiology conference in Orlando, talks about her efforts to learn more.

In animated films, nonhuman characters are still overwhelmingly male

2 days 20 hours ago
Female protagonists in animated films have come a long way over the past several decades. Take the 1959 movie "Sleeping Beauty": Soft-spoken and vulnerable, Princess Aurora is cursed as an infant by the evil fairy Maleficent and ultimately saved not by her own wits, but by a prince's kiss.

Newly discovered viruses reveal an evolutionary missing link

2 days 20 hours ago
Researchers at the University of Miami have identified a group of previously unknown viruses that bridge an evolutionary gap between viruses and cellular protein compartments, a discovery with implications for both biotechnology and scientists' understanding of the origins of life.
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