CNBC Business

Bernard Madoff masterminded the biggest investment fraud in U.S. history, ripping off tens of thousands of people of as much as $65 billion.

American Eagle Outfitters said its fiscal first-quarter revenue is on track to top $1 billion, thanks to strength at its namesake banner as well as Aerie.

These are the stocks posting the largest moves in midday trading.

Hollywood was dealt a crushing blow earlier this week when Decurion announced that its Pacific Theatres and ArcLight Cinema locations would close permanently.

American Airlines plans to grow its summer U.S. domestic capacity to more than 90% of 2019 levels.

Moderna CEO Stephane Bancel told CNBC the biotech firm hopes to have a booster shot for its Covid vaccine to protect against variants ready by the fall.

Ahead of Coinbase's market debut, bitcoin bull Mike Novogratz told CNBC that wealth generated by cryptocurrencies will continue to increase.

The Advisory Committee on Immunization Practices will review data on the women who developed a rare blood-clotting disorder.

Jeff Bezos' private space company Blue Origin launched and landed the fifteenth test flight of its New Shepard rocket booster and capsule on Wednesday.

Jeff Zients said the FDA's recommended pause on J&J's vaccine would not have a "significant impact" on the administration's vaccination program.

"There is a dearth of labor in the restaurant business and in the service business like we have never seen," said Charles Watson, Tropical Smoothie Cafe CEO.

Investors were looking for more green shoots in Bed Bath & Beyond's latest earnings.

Bed Bath & Beyond reported a double-digit decline in fourth-quarter sales, as ongoing store closures and divestments weigh on results.

With Covid-wary consumers pivoting to takeout and delivery, casual-dining restaurants like The Cheesecake Factory have struggled with falling sales.

Ryanair's CEO O'Leary used to be "one of the original skeptics" but says the airline is now focusing on greener initiatives.

The authorization comes as India faces a devastating new surge of Covid infections.

Europe's medicines regulator on Wednesday said it still believes the benefits of Johnson & Johnson's Covid-19 vaccine outweigh the risks of side effects.

Elon Musk's SpaceX added more money to its February equity raise, with the amended total reaching nearly $1.2 billion.

Investors poured $1.9 billion into space infrastructure companies in the first quarter of 2021, according to a report by New York-based firm Space Capital.

Kohl's said Wednesday it has come to an agreement with the group of activist investors who have been pushing to seize control of the retailer's board.