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Georgia Rep. Tom Price, Donald Trump's nominee to lead the federal agency that oversees Obamacare, is in the hot seat Wednesday both over his plan to revise the nation's health care system and his past financial investments.

Vice President-elect Mike Pence said Wednesday that Republicans do not yet have a bill to replace Obamacare, but that he has "seen a lot of great ideas" and that transition officials and GOP leaders are "getting very close" to having a replacement.

A teenage student in northeastern Mexico shot and wounded a teacher and three classmates at a private school before turning the gun on himself, authorities said.

The state of women in the time of Trump is ... fraught. I can't take credit for that insanely perfect word to describe this precarious time -- that goes to feminist writer and critic Roxane Gay.

It was a first for the entire world: Using a controversial in vitro fertilization technique, doctors in Kiev, Ukraine, helped a previously infertile couple conceive and deliver a baby girl. Some critics say, for genetic reasons, the use of this IVF method should have been restricted to producing a baby boy.

When asked what advice he's given Donald Trump, President Obama says he told the President-elect the office is of such magnitude that it's not a job you can do by yourself.

Noor Salman, widow of the man who killed 49 people at an Orlando gay nightclub last year, has pleaded not guilty in a federal court in California Wednesday to all charges filed against her. A grand jury this month charged Salman with obstruction of justice and aiding and abetting her husband's material support to ISIS, the Islamist terror group to which Mateen pledged allegiance before dying in a shootout with police. A bail hearing is set for February 1.

President Barack Obama talks about his decision to commute the sentence of Chelsea Manning during the final news conference of his presidency.

American Airlines is the latest airline to offer stripped-down airfare for a lower price.

Oklahoma is one of the more unlikely places in the United States to experience earthquakes. But in the six years that Scott Pruitt has served as the state's attorney general, Oklahoma has been rattled by hundreds of quakes with a magnitude of 3.0 and greater, with some areas facing the same level of risk as high-hazard parts of California.

No, Donald Trump, NBC's "Today" show is not doing "badly."

President Barack Obama will leave office Friday with his highest approval rating since 2009, his presidency largely viewed as a success, and a majority saying they will miss him when he is gone.

Chelsea Clinton has kept a low profile since her mother's election defeat in November.

The U.S. sued JPMorgan Chase Wednesday, accusing the nation's largest bank of paying some women tech workers less than their male counterparts.

Honey, it's happening.

The world's biggest oil company, Saudi Aramco, is still planning to go public next year.

Tom Oye credits his inflatable backpack for saving his life after after being swept up in an avalanche in Whistler, British Columbia.

CNN's Dr. Sanjay Gupta asks the Dalai Lama if he's optimistic about the U.S. after the presidential election.

The metro system and some schools in Italy's capital, Rome, were being evacuated Wednesday following a series of powerful earthquakes that struck the heart of the country.