CNN US

Senate Republicans continue to sound optimistic about their chances of passing their last, last-ditch attempt to repeal and replace Obamacare before their window to do so closes at the end of the month. (I'm more skeptical.)

CNN's Michael Holmes flies over the island of Dominica, which has been hit badly by Hurricane Maria.

Although Donald Trump has already launched is re-election campaign, only one Democrat so far -- Maryland Rep. John Delaney -- has thrown his hat in the 2020 ring. The vast majority of presidential prospects have remained coy about their plans -- but few have explicitly ruled out a White House bid.

As yet another hurricane descends into the Caribbean, vulnerable and often tourism-dependent nations are again being badly battered. Wednesday morning, Maria made landfall in Puerto Rico with 155-mph winds after devastating Dominica and other islands. After the physical impact, it will take years to rebuild; the long-term economic consequences will be even more devastating, if less obvious to the casual observer. As the destruction unfolds, the United States has a responsibility to help.

Allen Barron scrunches up his tiny face and wails as his mother gently tips him backward onto the lap of Jean Calvo, a pediatric dental resident at the University of California-San Francisco.

CNN's Brooke Baldwin analyzes moments on the Senate floor amid tension from the proposed Graham-Cassidy health care bill.

Democrats say they are planning to look into a report about Health and Human Services Secretary Tom Price taking five work-related trips on private jets last week, costing taxpayers tens of thousands of dollars more than had he flown commercial.

Sen. Susan Collins told CNN on Wednesday she was "disappointed" that a bipartisan health effort collapsed while the Republican-only Graham-Cassidy bill surged ahead instead.